RecruitingNot ApplicableNCT04846803

Bacterial Interference for Preventing Recurrent Urinary Tract Infection - New Ways of Treatment


Sponsor

Odense University Hospital

Enrollment

80 participants

Start Date

Jan 9, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Urinary tract infection (UTI) is one of the most common bacterial infections worldwide. It affects 150 million people annually. Treatment of patients with UTI entails a high consumption of antibiotics and large social and health costs. With this protocol, we want to elucidate alternative treatment methods for especially recurrent urinary tract infection. Bacteria have internal competitiveness (bacterial interference) and it is known that the non-pathogenic E.coli can outcompete the pathogenic E.coli in laboratory studies. We intend to strengthen the clinical evidence that it can be used as patient treatment through a clinical, placebo-controlled, double-blind trial at Odense University Hospital.


Eligibility

Min Age: 18 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a biological treatment called ABU bladder lavage and a biological treatment called Saline bladder lavage for people with recurrent urinary tract infections. The study is currently recruiting participants at 2 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BIOLOGICALABU bladder lavage

Clinical effect of preventive treatment (prophylactic treatment) - bladder lavage with the non-pathogenic bacterial strain (ABU)

BIOLOGICALSaline bladder lavage

Clinical effect of preventive treatment (prophylactic treatment) - bladder lavage with saline


Locations(2)

Aarhus University Hospital

Aarhus N, Denmark

Odense University Hospital

Odense C, Denmark

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NCT04846803


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