Bacterial Interference for Preventing Recurrent Urinary Tract Infection - New Ways of Treatment
Odense University Hospital
80 participants
Jan 9, 2024
INTERVENTIONAL
Conditions
Summary
Urinary tract infection (UTI) is one of the most common bacterial infections worldwide. It affects 150 million people annually. Treatment of patients with UTI entails a high consumption of antibiotics and large social and health costs. With this protocol, we want to elucidate alternative treatment methods for especially recurrent urinary tract infection. Bacteria have internal competitiveness (bacterial interference) and it is known that the non-pathogenic E.coli can outcompete the pathogenic E.coli in laboratory studies. We intend to strengthen the clinical evidence that it can be used as patient treatment through a clinical, placebo-controlled, double-blind trial at Odense University Hospital.
Eligibility
Plain Language Summary
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Interventions
Clinical effect of preventive treatment (prophylactic treatment) - bladder lavage with the non-pathogenic bacterial strain (ABU)
Clinical effect of preventive treatment (prophylactic treatment) - bladder lavage with saline
Locations(2)
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NCT04846803