RecruitingNCT04848870

Dental and Periodontal Status of Patients With Sjögren's Syndrome.

Prevalence and Characteristics of Dental and Periodontal Lesions in Patients With Sjögren's Syndrome. Establishment of a Biological Saliva Collection.


Sponsor

Assistance Publique - Hôpitaux de Paris

Enrollment

100 participants

Start Date

Jan 12, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

Sjögren's syndrome (SS) is a rare chronic systemic autoimmune disease characterized by destruction of the exocrine glands, including the salivary glands.The lack of saliva exposes the patient to dental caries, and dental wear although this has rarely been shown in Sjögren's patients. Moreover, these patients seem to have more inflammation and gingival recession, although this has not been clearly identified in the literature. Our main objective is to assess the prevalence of dental wear and gingival recession in patients with Sjögren's syndrome by analyzing of the Basic Erosive Wear Examination (BEWE) score for erosions, Basic Erosive Wear Abrasion (BEWA) score for attrition and percentage of sites with periodontal recessions greater than 3 mm in relation to the total number of sites. Our secondary objectives are to investigate a correlation between the prevalence of dental and gingival wear, gingival inflammation, Decayed, Missing, and Filled Teeth (DMFT) index and (1) salivary parameters and (2) oral quality of life. The salivary samples will be kept in a biological collection within the URP2496 for later analysis (biological collection CB-SJO).


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is examining the dental and gum health of patients with Sjögren's syndrome — an autoimmune disease that severely reduces saliva production, leading to dry mouth and a much higher risk of tooth decay and gum disease — to better understand and address these oral health complications. **You may be eligible if:** - You have been diagnosed with Sjögren's syndrome - You are over 18 years old - You are covered under a social security scheme - You can understand and read French well enough to review study information - You do not object to participating **You may NOT be eligible if:** - You have previously stated that you do not want to participate in the research Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERSalivary samples

collection of salivary samples from Sjögren patients on routine care in the oral medicine department.NA


Locations(1)

Service de Médecine bucco-dentaire

Ivry-sur-Seine, Île-de-France Region, France

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NCT04848870