RecruitingNot ApplicableNCT04856501

A Randomized Control Trial of a Responsive Parenting Intervention to Support Healthy Brain Development and Self-regulation in Toddlers Born Preterm


Sponsor

The University of Texas Health Science Center, Houston

Enrollment

300 participants

Start Date

Aug 7, 2020

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to determine whether participation in the Play and Learning Strategies (PALS) parenting intervention results in increased caregiver responsiveness behaviors and to test if participation in PALS results in increases in toddler skills and/or toddler neurological development.


Eligibility

Min Age: 15 MonthsMax Age: 30 Months

Inclusion Criteria1

  • \- Maternal age over 18-years when child was born

Exclusion Criteria9

  • presence of known/suspected congenital anomalies including chromosomal or complex congenital heart disease
  • congenital infection including TORCH (Toxoplasmosis, Rubella, Cytomegalovirus, Herpes Simplex and others),untreated maternal HIV, or maternal syphilis
  • bilateral grade 3/4 intraventricular hemorrhage,intraparenchymal hemorrhage, hydrocephalus
  • Cerebral palsy with Gross Motor Function Classification of III or higher
  • blindness-
  • deafness
  • Current maternal drug use or maternal drug use during pregnancy
  • families who reside outside the catchment area (>1 hour drive from the Texas Medical Center)
  • Child with contraindication for MRI. If the mother of the child is pregnant, thinks she might be pregnant, or has a contraindication for MRI, another relative of the child will be asked to assist with the MRIs

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Interventions

BEHAVIORALPALS intervention condition

The Play and Learning Strategies (PALS) intervention provides parents with behaviors that, collectively, are known as a responsive parenting style. Four constructs make up this responsive parenting style: 1) contingent responsiveness, (responses are conditionally linked to the child's signals) 2) warm sensitivity (high levels of affection and understanding of child states), 3) maintaining vs. redirecting attention, and 4) verbal scaffolding (providing child appropriate language supports). Parents assigned to this intervention will be paired with a coach who will guide them through the program over the course of 9 weekly sessions. The intervention (ePALS) will be implemented via an internet adaptation through the Children's Learning Institute's ENGAGE platform. However, ePALS could easily be adapted for other platforms and accessed with any web-enabled device.

BEHAVIORALControl condition

Families assigned to the control condition will be provided with a website with information corresponding to milestones of toddler development. Control families will be asked to review that week's materials before the each of the 9 weekly coach calls. The active control condition serves three important purposes: 1) Maintains an active line of communication and accurate contact records for Post-test 1 and Post-test 2 session scheduling; 2) Masks participant's awareness of intervention vs. control assignment; and 3) Approximates communication with intervention staff such that results showing ePALS effects are attributable to intervention rather than regular communication with an interventionist.


Locations(1)

The University of Texas Health Science Center at Houston

Houston, Texas, United States

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NCT04856501


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