RecruitingNot ApplicableNCT04861194

EREctile Function Preservation for Prostate Cancer Radiation Therapy (ERECT)

EREctile Function Preservation for Prostate Cancer Radiation Therapy (ERECT); a Prospective Phase II Trial


Sponsor

UMC Utrecht

Enrollment

70 participants

Start Date

Jul 14, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

Single-arm phase II trial of 70 men with low- or intermediate-risk prostate cancer receiving magnetic resonance guided adaptive radiotherapy (MRgRT) in 5 fractions of 7.25 Gy, additionally sparing the neurovascular bundles, the internal pudendal arteries, the corpora cavernosa, and the penile bulb for erectile function preservation.


Eligibility

Sex: MALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing different radiation techniques for prostate cancer to see which approach best preserves erectile function while still effectively treating the cancer. **You may be eligible if...** - You are 18 years or older - You have been diagnosed with low-risk or intermediate-risk prostate cancer confirmed by biopsy - You currently have normal or near-normal erectile function (based on a standard questionnaire) - You are in good general health **You may NOT be eligible if...** - Your prostate cancer is high-risk or has spread beyond the prostate - You already have significantly reduced erectile function - Your health status is too poor to tolerate radiation therapy Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

RADIATIONNeurovascular-sparing

Dose reduction of the neurovascular bundles, internal pudendal arteries, corpora cavernosa, and penile bulb during 5x7.25 Gy MRgRT


Locations(1)

University Medical Center Utrecht

Utrecht, Utrecht, Netherlands

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NCT04861194


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