RecruitingNot ApplicableNCT04864158

Prosthesis Versus Active Exercise Program in Patients With Rotator Cuff Arthropathy

Prosthesis Versus Active Exercise Program in Patients With Rotator Cuff Arthropathy Eligible For Reverse Shoulder Arthroplasty: the ReAct Multicenter, Randomized Controlled Trial


Sponsor

University of Aarhus

Enrollment

102 participants

Start Date

May 28, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

Reverse shoulder arthroplasty (RSA) is a well-established treatment for rotator cuff arthropathy. However, the effectiveness of RSA has not been compared to non-surgical treatment in a randomised controlled trial. Shoulder exercises may be an effective treatment for reducing pain and improving function in glenohumeral osteoarthritis. The primary aim of this trial is to examine if RSA followed by standard postsurgical rehabilitation is superior to a 12-week exercise programme in patients with rotator cuff arthropathy eligible for unilateral RSA. The investigators hypothesise that surgical intervention followed by standard rehabilitation, results in clinically relevant (14-point, on a scale from 0-100) improvement compared to the exercise intervention.


Eligibility

Min Age: 60 YearsMax Age: 85 Years

Inclusion Criteria3

  • Patients 60-85 years
  • Eligible for RSA
  • Rotator cuff arthropathy according to Hamada grade 3, 4 and 5 (33)

Exclusion Criteria7

  • Previous shoulder fracture (fracture of the proximal humerus or glenoid fracture)
  • Planned other upper extremity surgery within six months
  • Rheumatoid arthritis or other types of arthritis not diagnosed as primary glenohumeral OA
  • Cancer diagnosis and receiving chemo-, immuno- or radiotherapy
  • Neurological diseases affecting shoulder mobility (e.g. disability after previous stroke, multiple sclerosis, Parkinson's, Alzheimer's disease)
  • Other reasons for exclusion (i.e. mentally unable to participate) or planned absence for more than 14 days in the first 3 months after baseline test.
  • Unable to communicate in the participating countries respective languages

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Interventions

PROCEDURETSA-group

Reverse total shoulder arthroplasty followed by standard rehabilitation.

OTHERExercise-group

The exercise-group will attend a 12-week exercise program with one weekly physiotherapist-supervised session supplemented with two weekly sessions of home-based exercises. Utilisation of a predefined training protocol describing procedures and content of each session secure uniformity and standardisation of the intervention. The exercise program consists of two warm-up exercises and five exercises that target shoulder range of motion and muscle strength. Furthermore, a link to a video, informing about glenohumeral osteoarthritis, the role of exercise and exercise related pain, will be sent to all patients in the exercise-group. The physiotherapists delivering the exercise intervention are not otherwise related to the trial.


Locations(8)

Aarhus University Hospital

Aarhus N, Denmark

Esbjerg Hospital

Esbjerg, Denmark

Aalborg University Hospital

Farsø, Denmark

Silkeborg Regional Hospital

Silkeborg, Denmark

Viborg Regional Hospital

Viborg, Denmark

Tartu University Hospital

Tartu, Estonia

Tampere University Hospital

Tampere, Finland

Oslo University Hospital

Oslo, Norway

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NCT04864158


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