RecruitingNCT04865172

ECOCAPTURE for the Assessment of Apathy Under Real-life Conditions

ECOCAPTURE@HOME: Program for the Assessment of Behavioural Markers of Apathy Under Real-life Conditions Aimed At Patients with Neurodegenerative Dementias and Their Caregivers

Sponsor

Institut National de la Santé Et de la Recherche Médicale, France

Enrollment

120 participants

Start Date

May 20, 2022

Study Type

OBSERVATIONAL

Conditions

Alzheimer Disease Frontotemporal Dementia, Behavioral Variant

Summary

ECOCAPTURE@HOME is a study which is currently being developed with the objective to capture the behavioral signature of apathy in everyday life context through remote monitoring of participants' behavior for about one month. Participants will not only be patients with apathy but also their spouse caregiver. Behavioral markers of apathy will be extracted from a combination of: 1/ objective physiological data from sensors on a bracelet worn by participants; 2/ subjective data filled by the caregiver through an application. Thus investigators will collect a pool of metrics and show they can measure three assumed behavioral markers of apathy (daytime activity, quality of sleep and emotional arousal), which in turn allow to predict caregiver's perception of the dyad's psychological state. The final goal is to lay the foundations for the development of a clinical tool for the remote follow-up of patient-caregiver couples.

Eligibility

Min Age: 40 YearsMax Age: 85 Years

Plain Language Summary

Simplified for easier understanding

This study is using a special sensor-equipped room (called ECOCAPTURE) to measure apathy — a loss of motivation or interest — in people with Alzheimer's disease or frontotemporal dementia in real-life conditions, rather than just through questionnaires. **You may be eligible if...** - You have been diagnosed with frontotemporal dementia (bvFTD) or Alzheimer's disease - You have a Mini-Mental State Examination (MMSE) score of 10 or above - You are between 40 and 85 years old - You do not have any other brain conditions or psychiatric disorders **You may NOT be eligible if...** - Your cognitive impairment is very severe (MMSE below 10) - You have another psychiatric or neurological condition - You are outside the age range of 40–85 Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERRemote collection of passive and active data for 28 consecutive days

Passive sensor data: collected continuously for 28 days, from a multi-sensor wearable bracelet worn by each member of the dyad; Active questionnaire data: collected once a week during the four weeks of monitoring (and at the end of the 28 days for patient-caregiver dyads), from questionnaires filled by one partner of the dyad (for patient-caregiver dyads, this will be the caregiver) using a smartphone application.

Locations(1)

ICM, Hôpital Salpêtrière

Paris, France

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NCT04865172

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