rTMS Efficacy Coupled With Mirror Therapy
Clinical Study of Repetitive Transcranial Magnetic Stimulation (RTMS) Efficacy Coupled With Mirror Therapy for Neuropathic Pain Relief
Centre Hospitalier Universitaire de Saint Etienne
64 participants
Oct 27, 2022
INTERVENTIONAL
Conditions
Summary
Neuropathic pain is particularly difficult to treat with classic first-line drugs. Neuromodulation techniques using repetitive transcranial magnetic stimulation (rTMS) are useful alternative, but there is a need to improve their analgesic effect.Virtual reality mirror therapy has shown the capacity to alleviate pain and may be easily coupled with rTMS.The present project will investigate in individuals with neuropathic pain the effects of the rTMS coupled with virtual reality mirror therapy.
Eligibility
Inclusion Criteria4
- Clinical symptoms typical of neuropathic pain
- Refractory to drug therapies
- Lasting for at least 6 months, with a moderate to severe pain intensity (≥4/10 on Visual Analog Scale, VAS) and a stable pain treatment since 1month at least
- Having right to health benefits
Exclusion Criteria3
- Ferromagnetic components and implanted microprocessors (i.e. cochlear implants)
- Drug-resistant or active epilepsy, pacemaker, pregnancy, ongoing depression or personality troubles, and ongoing opioid treatment.
- Any other contraindications to MRI scanner (e.g., claustrophobia, etc.).
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Interventions
20 minutes of high frequency (20Hz) rTMS.
active mirror-based therapy
20 minutes of sham mirror-based therapy
Locations(2)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT04867187