RecruitingNCT04867915

Study on the Diagnosis and Management of CLL in Italy by GIMEMA

Observational Study on the Diagnosis and Management of Chronic Lymphocytic Leukemia (CLL) in Italy by Gruppo Italiano Malattie EMatologiche Dell'Adulto (GIMEMA)

Sponsor

Gruppo Italiano Malattie EMatologiche dell'Adulto

Enrollment

12,500 participants

Start Date

Oct 13, 2021

Study Type

OBSERVATIONAL

Conditions

Chronic Lymphocytic Leukemia Small Lymphocytic Lymphoma MBL-CLL - Monoclonal B-Cell Lymphocytosis Chronic Lymphocytic Leukaemia-Type

Summary

retrospective and prospective multicenter observational clinical and biological data collection from all patients with newly diagnosed CLL, SLL or MBL. retrospective cohort: all cases with a diagnosis between January 1st 2010 and August 31th 2021. prospective cohort: all patients with a diagnosis between September 1st 2021 and September 1st 2025.

Eligibility

Min Age: 18 Years

Inclusion Criteria8

Age ≥18 years at diagnosis
One of the following diagnoses that meet the international diagnostic criteria (iwCLL2018 and WHO2017)
Chronic lymphocytic leukemia (CLL)
Small lymphocytic lymphoma (SLL)
CLL-like monoclonal B-cell lymphocytosis (MBL)
Retrospective cohort: CLL/SLL/MBL diagnosis between January 1st 2010 and August 31th 2021.
Prospective cohort: CLL/SLL/MBL diagnosis between September 1st 2021 and September 1st, 2025.
Signed written informed consent according to ICH/EU/GCP and national local laws (if applicable)

Exclusion Criteria1

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Locations(24)

Aon Ss. Antonio E Biagio E C. Arrigo - Alessandria - Soc Ematologia

Alessandria, Italy

Asst Degli Spedali Civili Di Brescia - Ssvd Centro Trapianti Midollo Per Adulti - Cattedra Di Ematologia

Brescia, Italy

Asl Brindisi, Ospedale 'Perrino' - Brindisi - Uo Ematologia

Brindisi, Italy

Fondazione Del Piemonte Per L'Oncologia Centro Trapianti

Candiolo, Italy

SOD ematologia AOU Careggi

Florence, Italy

Ao Ospedali Riuniti "Papardo Piemonte" - Po Papardo - Messina - Sc Ematologia

Messina, Italy

UOC Ematologia AOU Policlinico "G. Martino"

Messina, Italy

Aulss 3 Serenissima, Ospedale Dell'Angelo - Mestre - Uo Ematologia

Mestre, Italy

Fondazione Irccs "Istituto Nazionale Tumori" - Milano - Sc Ematologia

Milan, Italy

Fondazione Irccs Ca' Granda, Ospedale Maggiore Policlinico - Milano - Ematologia - Padiglione Marcora

Milan, Italy

Ospedale San Raffaele

Milan, Italy

Asl Di Piacenza, Ospedale "Guglielmo Da Saliceto" - Ematologia E Centro Trapianti

Piacenza, Italy

UOSD Ematologia Giovanni Paolo II

Ragusa, Italy

Fondazione Policlinico Universitario Agostino Gemelli Irccs - Roma - Area Ematologica

Roma, Italy

Aou "San Giovanni Di Dio E Ruggi D'Aragona" - Salerno - Uoc Ematologia E Trapianti Di Cellule Staminali Emopoietiche

Salerno, Italy

Ente Ecclesiastico Casa Sollievo Della Sofferenza - San Giovanni Rotondo - Ematologia

San Giovanni Rotondo, Italy

Aou Senese - Uoc Ematologia E Trapianti

Siena, Italy

Ao S. Maria - Terni - Sc Onco Ematologia

Terni, Italy

Aou Città Della Salute E Della Scienza, Ospedale S. Giovanni Battista Molinette - Torino - Sc Ematologia - Università Degli Studi Di Torino

Torino, Italy

Aou Città Della Salute E Della Scienza, Ospedale S. Giovanni Battista Molinette - Torino - Sc Ematologia 2

Torino, Italy

Asl to 2, Torino Nord Emergenza San Giovanni Bosco - Ssd Ematologia

Torino, Italy

UOC Ematologia PO Treviso

Treviso, Italy

UCO Ematologia ASUGI Trieste

Trieste, Italy

Aulss 8 Berica - Ospedale Di Vicenza - Uoc Ematologia

Vicenza, Italy

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NCT04867915

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