RecruitingPhase 2NCT04881682
Immunoadsorption Versus Immunoglobulins for Treatment of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)
Sponsor
University of Ulm
Enrollment
20 participants
Start Date
May 1, 2023
Study Type
INTERVENTIONAL
Conditions
Summary
This is a randomized controlled study evaluating safety and efficacy of repeated immunoadsorption versus immunoglobulins in steroid-refractory Chronic Inflammatory Demyelinating Polyneuropathy (CIDP).
Eligibility
Min Age: 18 Years
Plain Language Summary
Simplified for easier understanding
This study is comparing two treatments for CIDP (Chronic Inflammatory Demyelinating Polyneuropathy) — a condition where the immune system attacks the nerves, causing weakness and numbness. The two treatments being compared are immunoadsorption (a process that filters harmful antibodies from the blood) and intravenous immunoglobulins (IVIG, which boosts the immune system in a different way).
You may be eligible if:
- You are 18 years or older
- You have been diagnosed with CIDP (possible, probable, or definite) for 3 years or less
- You have already tried corticosteroids (methylprednisolone) and either did not respond well, had significant side effects, or have a reason you cannot take them
You may NOT be eligible if:
- You have signs of an active serious infection (high CRP or a urinary tract infection)
- You have taken an ACE inhibitor within the past week
- You have IgA deficiency
- You have other contraindications to immunoadsorption or IVIG
Talk to your doctor to see if this trial is right for you.
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
DEVICEImmunoadsorption
see arm/group description
BIOLOGICALImmunoglobulins
see arm/group description
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT04881682
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