Dynamics of Markers of Infection and Inflammation in Hospitalized Coronavirus Disease 2019 (COVID-19) Patients
Dynamics of Nucleocapsid Antigen Serum Levels and Other Markers of Infection and Inflammation in Hospitalized Coronavirus Disease 2019 (COVID-19) Patients - a Pilot Study
University Hospital Hradec Kralove
30 participants
Apr 1, 2021
OBSERVATIONAL
Conditions
Summary
Patients requiring admission to the hospital due to a moderate and severe COVID-19 infection may differ in their ability to respond to viral infection and to eliminate viral load. Several comorbidities and interventions like antivirotic or antiinflammatory treatment may also modify expected patients response and decrease of viral load. In this observational study, evolution of selected inflammatory markers, indicators of severity of infection and patient characteristics will be followed and recorded in hospitalized patients with COVID-19.
Eligibility
Inclusion Criteria3
- SARS CoV2 positive test within last 14 day
- bilateral infiltrates on chest X.ray or CT
- need for oxygen to keep pulse oximetry saturation above 92% or other respiratory support measures (HFNO, non-invasive ventilation or invasive ventilation)
Exclusion Criteria2
- known history of intersticial lung disease
- known history of congestive heart failure
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Locations(1)
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NCT04887623