Efficacy and Safety Evaluation of the Treatment of Allergy Against Cupressaceae and Grasses.

This trial is evaluating the effectiveness and safety of allergy immunotherapy (allergy drops or shots) targeting both cypress tree pollen and grass pollen in people allergic to both. The goal is to reduce allergy symptoms like sneezing, runny nose, and itchy eyes during the pollen season. **You may be eligible if...** - You are between 12 and 65 years old - You have confirmed moderate-to-severe allergic rhinitis or rhinoconjunctivitis caused by both cypress and grass pollen - Your skin prick test and blood IgE test confirm allergies to both cypress and grass pollen - You do not have significant allergies to other common airborne allergens - Women of childbearing age must use effective contraception and have a negative pregnancy test - You have a smartphone to record daily symptoms **You may NOT be eligible if...** - You are allergic to multiple other environmental allergens (dust mites, mold, pets) - You have received allergy immunotherapy in the past 5 years - You have severe or poorly controlled asthma (breathing test FEV1 below 70%) - You are taking beta-blocker medications - You have autoimmune disease, significant organ disease, or a serious psychiatric disorder - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.