Trial of Center-Based vs. In-Home Pivotal Response Treatment (PRT) in Autism

This study is comparing two versions of Pivotal Response Treatment (PRT) — a behavioral therapy for young children with autism — delivered either at a clinic (center-based) or in the child's home. PRT teaches communication and social skills through natural play-based interactions. The goal is to find out whether in-home therapy is just as effective as clinic-based therapy, which could make treatment more accessible to families. You may be eligible if: • Your child has been diagnosed with Autism Spectrum Disorder (ASD) based on standard diagnostic tools • Your child is between 2 years and 5 years 11 months old • Your child has a language delay based on standardized testing (PLS-5 score below age-level norms) • Any current therapies, medications, or school placements have been stable for at least 1 month • At least one parent or caregiver can consistently participate in the program • Your child receives no more than 60 minutes of individual speech therapy per week • Your family lives within 30 miles of Stanford University You may NOT be eligible if: • Your child has a current diagnosis of a severe psychiatric disorder (e.g., bipolar disorder) • Your child is receiving 15 or more hours of ABA therapy per week • Your child has an active medical problem such as unstable seizures or heart disease • Your child has previously received an adequate trial of PRT • Your child's primary language is not English Talk to your doctor to see if this trial is right for you.