Conception of a Diagnosis, Prognosis and Therapeutic Decision Tool for Patients With Autoimmunity and Inflammation

This study builds a database and decision-support tool for children with rare immune system disorders that cause autoimmunity or inflammation. By collecting detailed health and genetic information, researchers aim to improve how these diseases are diagnosed and treated. **You may be eligible if...** - You are a child under 18 years old (or a healthy control/relative of a patient) - You are being treated at Necker Hospital in France for a primary immune disorder with autoimmunity or inflammation (such as lupus, juvenile arthritis, severe EBV infection, or related genetic conditions) - A parent or guardian has signed informed consent **You may NOT be eligible if...** - You have received antibiotics within the past 2 weeks - You are undergoing cytotoxic cancer chemotherapy or antiviral treatment - You are in a life-threatening condition in the short term - A parent or guardian has not consented Talk to your doctor to see if this trial is right for you.