RecruitingPhase 2NCT04905056

A Prospective, Two-center, Single Arm Phase II Clinical Study to Evaluate Safety and Effectiveness of Ablation Therapy in the Treatment of Lung Cancer Presenting as Ground-glass Nodules


Sponsor

Shanghai Zhongshan Hospital

Enrollment

120 participants

Start Date

Jan 1, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

A prospective, two-center, single arm phase II clinical study to evaluate safety and effectiveness of ablation therapy in the treatment of lung cancer presenting as ground-glass nodules


Eligibility

Min Age: 18 YearsMax Age: 85 Years

Plain Language Summary

Simplified for easier understanding

This study evaluates a minimally invasive treatment called ablation therapy (using heat or cold to destroy tissue) for small lung abnormalities called ground-glass nodules (GGNs) — hazy areas seen on CT scans that may be early lung cancer — in patients who cannot have or choose not to have surgery. **You may be eligible if...** - You are between 18 and 85 years old - A CT scan shows a ground-glass nodule in your lung that has not resolved after 3 months - The nodule is between 8mm and 3cm in size - The nodule has shown growth or increased density over time - You cannot tolerate standard surgery, have multiple nodules, or have already had surgery on the same side of the chest **You may NOT be eligible if...** - You have been in another clinical trial within the past month - You have severe other illnesses - You have an allergy to anesthesia drugs - You have another autoimmune disease - You cannot cooperate with the research team Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERAblation therapy

Ablation therapy in the treatment of lung cancer presenting as ground-glass nodules


Locations(1)

Department of Thoracic Surgery, Zhongshan Hospital, Fudan University

Shanghai, Shanghai Municipality, China

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NCT04905056


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