RecruitingNCT04905537
Study on Early Genetic Screening and Precise Strategy of Neonatal Critical Illness
Sponsor
Children's Hospital of Fudan University
Enrollment
4,000 participants
Start Date
Jan 1, 2021
Study Type
OBSERVATIONAL
Conditions
Summary
The researchers hope to establish an overall program of early genetic screening for neonatal critical illness in China, and to develop precise intervention strategies to assist clinical diagnosis and treatment of hereditary critical illness.
Eligibility
Max Age: 100 Days
Inclusion Criteria4
- Postnatal age less than 100 days;
- Perinatal death after 20 weeks of gestation (more than 500 g)
- Can be retained biological samples for genetic screening;
- Biological parent or guardian's informed consent.
Exclusion Criteria8
- Reluctance of parents to use genetic sequencing data for subsequent research;
- Parents under 18 years of age or incapacitated for decision-making;
- subjects older than 100 days;
- Perinatal death less than 20 weeks of gestation or weight less than 500 g;
- Inherited metabolic diseases with chromosomal abnormalities;
- Multiple pregnancies;
- Lack of access to biological samples from which DNA can be extracted;
- Failure to sign informed consent.
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Interventions
OTHERNo intervention
It's only observational study. No interventions.
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT04905537
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