High Dose Omeprazole in Patients With Pancreatic Cancer

This study investigates whether taking high doses of omeprazole (a common heartburn/acid-reflux medication) before surgery might help fight pancreatic cancer by making the tumor's environment more acidic and less favorable to cancer cells. **You may be eligible if...** - You have been newly diagnosed with pancreatic cancer (adenocarcinoma type), confirmed by imaging or biopsy - You are a candidate for surgical removal of your pancreatic cancer - You are 18 or older and in generally good health (ECOG 0-2) - You are not pregnant **You may NOT be eligible if...** - Your pancreatic cancer cannot be surgically removed - You have already had surgery for pancreatic cancer - You are pregnant or breastfeeding - You have a serious allergy or medical condition that prevents participation Talk to your doctor to see if this trial is right for you.