RecruitingNot ApplicableNCT04942093

NUTritional Impact of a Hypocaloric Hyperprotein Diet Before Obesity Surgery


Sponsor

University Hospital, Rouen

Enrollment

200 participants

Start Date

Oct 9, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

Obesity is a major public health problem and is constantly on the rise. Therapeutic approaches based on dietary advice, physical activity and the management of psychological difficulties are not always sufficient to achieve a lasting weight reduction. Bariatric surgery (or obesity surgery), accompanied by therapeutic education and adequate medical and dietary monitoring, can lead to significant and lasting weight loss. It is indicated as a second-line treatment for patients who have failed medical treatment, whose BMI is greater than or equal to 40 or whose BMI is greater than or equal to 35 with comorbidities (type 2 diabetes, arterial hypertension, obstructive sleep apnoea-hypopnoea syndrome, severe joint disorders). The surgeon may be very bothered by the intra-abdominal fat mass and especially by steatotic hepatomegaly (increase in the size of the liver and its fat load). Faced with this problem, various preoperative strategies such as the placement of an intra gastric balloon have been tried to decrease the size of the liver but a systematic review from 2016 indicates that a low calorie diet is preferable. Preoperative weight loss can reduce fat load and liver volume very rapidly. This meta-analysis shows that all low-calorie, high-protein diets are effective and that the optimal duration (4 weeks), compliance and tolerance are important factors for success.


Eligibility

Min Age: 18 YearsMax Age: 65 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying With low-calorie, high-protein diet and Without low-calorie, high-protein diet for people with bariatric surgery candidate, diet, healthy, and other related conditions. The study is currently recruiting participants at 3 locations.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIETARY_SUPPLEMENTWith low-calorie, high-protein diet

A low-calorie, high-protein diet will be prescribed to the patient for a period of 4 weeks. The diet will be done the 4 weeks before the bariatric surgery

DIETARY_SUPPLEMENTWithout low-calorie, high-protein diet

A low-calorie, high-protein diet will not be prescribed to the patient for a period of 4 weeks.


Locations(3)

Ch Dieppe

Dieppe, France

HPE

Le Havre, France

CHU de ROUEN

Rouen, France

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NCT04942093


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