RecruitingNCT04948437

Urinary Exosomal Biomarkers of Thyroglobulin and Galectin-3 for Prognosis and Follow-up in Patients of Thyroid Cancer

Urinary Exosomal Biomarkers of Thyroglobulin and Galectin-3 for Prognosis and Follow-up in Patients of Well-differentiated Thyroid Cancer


Sponsor

National Taiwan University Hospital

Enrollment

103 participants

Start Date

Aug 19, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

Now, the investigators carried out a prospective study enrolling patients with thyroid cancer, who had received ablative thyroidectomy and /or radioactive iodine therapy for two more years. The investigators' study already enrolled seventy-three patients with thyroid cancer, and the investigators plan to enroll 30 new patients in this consecutive research study. All patients received total thyroidectomy under clinically surgical judgement in initial therapeutic option. The investigators also further found some difference between papillary thyroid cancer and follicular thyroid cancer, and the investigators will continue annually to closely monitor the change of U-Ex Tg and urinary exosomal galectin-3 between differently cellular types of thyroid cancers.


Eligibility

Min Age: 20 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study is investigating whether thyroid cancer-related proteins (thyroglobulin and galectin-3) found in urine can serve as useful markers for monitoring how well thyroid cancer treatment is working — potentially offering a non-invasive alternative or complement to standard blood tests. **You may be eligible if...** - You have been diagnosed with papillary, follicular, or anaplastic thyroid cancer - You have already had surgery and are in the post-operative follow-up phase **You may NOT be eligible if...** - Your thyroid cancer diagnosis is not clearly confirmed (unclear or uncertain diagnosis) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Chih-Yuan Wang, M.D

Taipei, Taiwan

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NCT04948437


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