RecruitingPhase 1NCT04969042

Closed-loop Functional Spinal Cord Stimulation in Patients With Spinal Cord Injury

Efficacy of Closed-loop Functional Spinal Cord Stimulation on Walking Rehabilitation in Patients With Spinal Cord Injury


Sponsor

Luming Li

Enrollment

10 participants

Start Date

Aug 1, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this experiment is to evaluate the efficacy of Closed-loop Functional Spinal Cord Stimulation on Walking Rehabilitation in Patients after Spinal Cord Injury


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Inclusion Criteria7

  • Age 18~70
  • Spinal cord injury staging(AIS) A,B,C or D
  • Level of lesion is T10 and above
  • Distance between lesion and conus >60mm
  • Injured Time > 3 months
  • Capable of participating rehabilitation program
  • Agree to comply with all conditions of the study and to attend all required study training and visits

Exclusion Criteria9

  • With Obvious psychiatric disorder that cannot complete relevant questionaires
  • Cognitive impairment
  • Severe autonomic reflex disorder
  • Severe muscle atrophy and joint contracture
  • Cannot participate in spinal cord stimulation surgery or follow-up visits
  • Life expectancy less than 12 months
  • Abnormal blood or other physiological examinations that cannot conduct surgery, such as blood coagulation disorder or kidney/liver abnormalities
  • Uncontrollable hypertension, heart diseases, respiratory diseases or took related medicine in last 3 months
  • Unsuitable candidates in PI's perspective

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Interventions

DEVICEPins Medical G122 RS

G122RS model implanted spinal cord stimulation device, which could give closed-loop functional stimulation in the epidural space


Locations(1)

National Engineering Laboratory for Neuromodulation

Beijing, Beijing Municipality, China

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NCT04969042


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