RecruitingPhase 4NCT04991493

Effect of Tramadol on Postoperative Sore Throat After General Anesthesia

Effect of Tramadol on Postoperative Sore Throat in Thyroid Surgery Under General Anesthesia With Endotracheal Intubation: A Randomized Controlled Trial


Sponsor

Affiliated Cancer Hospital of Shantou University Medical College

Enrollment

168 participants

Start Date

Sep 10, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

Post operative sore throat after general anesthesia with endotracheal intubation is a common problem causing dissatisfaction and discomfort to the patients. The investigators want to study the effect of tramadol on postoperative sore throat in general anesthesia with endotracheal intubation.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 65 Years

Inclusion Criteria1

  • \- Female with American Society of Anesthesiologists (ASA) physical status I-II; Elective thyroidectomy(non-endoscopic) with endotracheal intubation; The patient signed the consent form.

Exclusion Criteria1

  • \- History of thyroid surgery A history of preoperative sore throat; Pregnancy; Retrosternal goiter; Thyroid tumor invading trachea need trachea reconstruction; Potentially difficult airway; Clinical diagnosis of chronic sore throat; Clinical diagnosis of psychosis; Tracheotomy after operation; Transfer to intensive care unit after operation; Contraindications to tramadol; Body mass index (BMI) > 30kg/m\^2.

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Interventions

DRUGTramadol hydrochloride

pre-tramadol group: 1mg/kg of tramadol will be intravenously injected 15 minutes before anesthesia. post-tramadol group: 1mg/kg of tramadol will be intravenously injected when the incision was washed and sutured.

OTHERNormal Saline

pre-tramadol group: Normal Saline will be injected intravenously when the incision was washed and sutured. post-tramadol group: Normal Saline will be injected intravenously 15 minutes before anesthesia.


Locations(1)

Affiliated Cancer Hospital of Shantou University Medical College Medical

Shantou, Guangdong, China

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NCT04991493


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