RecruitingNCT05014802

Baseline Atrial Fibrosis Predicts Risk for Post-operative Atrial Fibrillation in Patients Undergoing Cardiac Surgery

Baseline Atrial Fibrosis Predicts Risk for Post-operative Atrial Fibrillation in Patients Undergoing Cardiac Surgery: A Pilot Study for SAPPORO-AF

Sponsor

Tulane University

Enrollment

50 participants

Start Date

Nov 21, 2021

Study Type

OBSERVATIONAL

Conditions

Atrial Fibrillation Atrial Flutter Atrial Arrhythmia Atrial Tachycardia

Summary

The study aims to evaluate and compare the incidence of atrial arrhythmias (including Post-Operative Atrial Fibrillation (POAF), atrial flutter, and atrial tachycardia) stratified by baseline Utah fibrosis stages and overall fibrosis (%) of the left atrial wall area. The investigators hypothesize that patients with a higher baseline Utah fibrosis staging will experience a higher incidence of POAF. The study also aims to evaluate and compare the in-hospital mortality, length-of-stay (LOS), complication rates (strokes, pneumonia, respiratory failure etc.) of the different Utah fibrosis stage cohorts. Perform cost analysis and compare between patients with POAF and patients without POAF. The investigators hypothesize that patients experiencing POAF will have a higher mortality rate, longer LOS, greater complications, and therefore, additional hospital costs.

Eligibility

Min Age: 40 YearsMax Age: 120 Years

Plain Language Summary

Simplified for easier understanding

This study investigates whether scarring (fibrosis) in the upper chambers of the heart before surgery can predict which patients develop an irregular heart rhythm called atrial fibrillation after heart surgery. Researchers will use MRI to measure fibrosis levels beforehand. **You may be eligible if...** - You are 40 years or older (male or female) - You have NO history of any irregular heart rhythm (atrial fibrillation, atrial flutter, or atrial tachycardia) - You are scheduled for heart surgery such as bypass surgery (CABG), heart valve repair, aneurysm repair, or pacemaker placement **You may NOT be eligible if...** - You have a prior history of atrial fibrillation, atrial flutter, or atrial tachycardia - You cannot undergo cardiac MRI - You have metal implants or other contraindications to MRI Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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