RecruitingNCT05015231

Multiparametric MRI for Assessment of Changes of Renal Hemodynamics After Fistula Closure in Kidney Transplant Patients

Multiparametric MRI for Assessment of Changes of Renal Hemodynamics After Fistula Closure in Kidney Transplant Patients: a Pilot Study


Sponsor

University of Zurich

Enrollment

30 participants

Start Date

Aug 1, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

Assessment of changes of renal hemodynamics by multiparametric MRI after closure of AVF access.


Eligibility

Min Age: 18 Years

Inclusion Criteria6

  • Written informed consent
  • Age > 18 years
  • Patients wishing to close the fistula and planned for surgical fistula closure
  • eGFR CKD EPI ≥ 45 ml/min/1.73m2 at one year post transplantation
  • Stable eGFR within the past 6 months
  • Controlled blood pressure

Exclusion Criteria7

  • Kidney Transplantation < 12 months before fistula closure
  • Proteinuria > 500mg/d
  • Presence of donor specific antibodies
  • Rejection within the past 6 months
  • BK virus replication within the past 3 months
  • Cardiac pacemaker, which is not compatible with MRI
  • Claustrophobia

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Interventions

DIAGNOSTIC_TESTEchocardiography and MRI

Echocardiography and renal MRI before and after fistula closure


Locations(1)

University Hospital Zurich

Zurich, Switzerland

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NCT05015231


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