RecruitingNCT05019664

Affixus Natural Nail System Humeral Nail PMCF

Post-market Clinical Follow-up Study to Provide Safety, Performance and Clinical Benefits Data of the Affixus Natural Nail System Humeral Nail (Implants and Instrumentation)


Sponsor

Zimmer Biomet

Enrollment

100 participants

Start Date

Aug 29, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

A commercially available product clinical study which aims to confirm the safety, performance and clinical benefits to the patient of the Affixus Natural Nail upper arm (humerus) bone nail system for both the implant itself and the instrumentation used during surgery.


Eligibility

Min Age: 18 Years

Inclusion Criteria6

  • Patients 18 years or older and skeletally mature.
  • Patient must have either a proximal humeral fracture or humeral shaft fracture requiring surgical intervention and be eligible for fixation by intramedullary nailing.
  • Patient has been or is scheduled to be treated with the Affixus Natural Nail System Humeral Nail.
  • Patient must be able and willing to complete the protocol required follow-up.
  • Patient must have a signed Institutional Review Board/Ethics Committee approved informed consent. (An Institutional Review Board/Ethics Committee is group that has been formally designated to review and monitor medical research involving human subjects.)
  • Patients capable of understanding the surgeon's explanations and following his instructions, able and willing to participate in the follow-up program and who gave consent to take part in the study.

Exclusion Criteria12

  • Distal fracture involving the olecranon fossa.
  • Bone shaft having excessive bow or deformity.
  • A medullary canal obliterated by a previous fracture or tumor.
  • Active or previous infection.
  • Skeletally immature patients.
  • All concomitant diseases that can impair the functioning and the success of the implant.
  • Patients with mental or neurologic conditions who are unwilling or incapable of giving proper informed consent and following postoperative care instructions.
  • Patient is a vulnerable subject (prisoner, mentally incompetent or unable to understand what participation to the study entails, a known alcohol or drug abuser, anticipated to be non-compliant).
  • Patient known to be pregnant or breast feeding.
  • Likely problems with maintaining follow-up program (e.g. patient with no fixed address, long distance, plans to move during course of study).
  • Patients who have any condition that would in the judgment of the investigator place the patient at undue risk or interfere with the study.
  • Not expected to survive the duration of the follow-up program.

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Interventions

DEVICEhumeral fracture

Patient with either a proximal humeral fracture or humeral shaft fracture requiring surgical intervention and be eligible for fixation by intramedullary nailing.


Locations(5)

University of Texas Health Science Center at San Antonio

San Antonio, Texas, United States

UZ Leuven - Traumatology Department

Leuven, Belgium

Hospital de la Santa Creu i Sant Pau

Barcelona, Spain

General Foundation of the University of Valladolid

Valladolid, Spain

Kantonsspital Frauenfeld

Frauenfeld, Thurgau, Switzerland

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NCT05019664


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