PSMA Guided Approach for bIoCHEmical Relapse After Prostatectomy-PSICHE

This study tests whether using a specialized PET scan (68Ga-PSMA PET/CT) to precisely locate where prostate cancer has returned after surgery can help guide more targeted salvage treatment, potentially improving outcomes. **You may be eligible if...** - You previously had your prostate removed (radical prostatectomy) for prostate cancer - Your PSA (a blood marker for prostate cancer) is between 0.2 and 1.0 ng/ml — indicating a biochemical relapse (cancer coming back) - You may or may not have had post-surgery radiation already - Your doctor has recommended a PSMA PET/CT scan as part of standard re-staging **You may NOT be eligible if...** - You received androgen deprivation therapy (hormone therapy) within the last 6 months - Your PSA remained elevated immediately after surgery (above 0.1 ng/ml within 16 weeks of surgery), indicating incomplete removal Talk to your doctor to see if this trial is right for you.