RecruitingNCT05022914

PSMA Guided Approach for bIoCHEmical Relapse After Prostatectomy-PSICHE

Prostate-Specific Membrane Antigen (PSMA) Guided Approach for bIoCHEmical Relapse After Prostatectomy- A Prospective Observational Study-PSICHE


Sponsor

Azienda Ospedaliero-Universitaria Careggi

Enrollment

180 participants

Start Date

Jan 19, 2021

Study Type

OBSERVATIONAL

Conditions

Summary

This observational study was designed to evaluate progression free survival after PSMA-PET/CT based salvage approach for patients affected by biochemical relapse after radical prostatectomy.


Eligibility

Sex: MALEMin Age: 18 Years

Inclusion Criteria3

  • Signed informed consent
  • Age \>18
  • Patient suitable for 68Ga-PSMA PET/CT re-staging according to clinical practice (Previous radical prostatectomy with histological result of Prostate adenocarcinoma +/- postoperative prostate bed radiotherapy (adjuvant or salvage setting), with a biochemical relapse defined as a PSA \> 0.2 and \<1

Exclusion Criteria2

  • ADT administration within 6 months from study enrollment
  • Persistent elevation of PSA after RP measured within 16 weeks from surgery (\> 0.1 ng/ml)

Locations(1)

AOU Careggi Radiation Oncology Unit

Florence, Italy

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NCT05022914


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