RecruitingNCT05024175

Long-term Follow-up of Subjects Treated With CAR T Cells


Sponsor

Marcela V. Maus, M.D.,Ph.D.

Enrollment

45 participants

Start Date

Aug 7, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

This is a single site, non-randomized, open-label, long-term safety and efficacy follow-up study for Phase 1 studies that evaluate the safety and efficacy of CAR T cells: NCT05660369 (DF/HCC# 22-175) and NCT06026319 (DF/HCC# 23-474).


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is following patients long-term after they received CAR T-cell therapy — a type of cancer immunotherapy that uses genetically modified immune cells — in another clinical trial. The goal is to monitor health outcomes and any late-developing effects over many years. You may be eligible if: - You are 18 years or older - You received CAR T-cell therapy as part of an approved clinical trial at DF/HCC - You provided voluntary written informed consent You may NOT be eligible if: - You are unable to comply with the study requirements Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTDisease assessments

CT (Computerized Tomography) scan or PET-CT (Positron Emission Tomography-Computerized Tomography) scans as per protocol

PROCEDURETumor Biopsy

Tumor Biopsy per protocol

DIAGNOSTIC_TESTBlood test

Blood Test per protocol


Locations(1)

Massachusetts General Hospital

Boston, Massachusetts, United States

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NCT05024175


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