SPIROMICS Study of Early COPD Progression (SOURCE)

This large study (SOURCE) follows current or former smokers in the early stages of COPD (chronic obstructive pulmonary disease) — a lung condition that makes breathing difficult — as well as healthy non-smokers. The goal is to understand what factors cause COPD to progress quickly versus slowly, which could help develop earlier interventions. **You may be eligible if...** - You are 30–55 years old - You are a smoker or former smoker with at least 10 pack-years of smoking history (or a healthy non-smoker for the control group) - You have normal or mildly reduced lung function (early or pre-COPD), OR you are a healthy non-smoker with normal lungs **You may NOT be eligible if...** - You have severe asthma - You have very advanced COPD (severe airflow limitation) - You have significant other lung diseases unrelated to smoking - You are unwilling or unable to complete the required visits and tests Talk to your doctor to see if this trial is right for you.