The Brain Mechanism of Social Emotion and Communication in Infants Aged 0 to 6 Years
A Cohort Study on the Brain Mechanism of Social Emotion and Communication in Infants Aged 0 to 6 Years
Children's Hospital of Fudan University
3,001 participants
Aug 1, 2021
OBSERVATIONAL
Conditions
Summary
This study explores the relationship between brain development and infants' social emotion and communication ability, as well as the role of genetic factors and maternal exposure during pregnancy (e.g., environmental exposures and maternal inflammatory states). To provide a theoretical basis for precise intervention of infants' social emotion and communication problems and the overall improvement of brain development.
Eligibility
Inclusion Criteria5
- Age 0-6 years
- Born at 34-42 weeks of gestation
- Birth weight\>1500g
- Normal brain function assessment
- Parents can understand and sign informed consent
Exclusion Criteria6
- The mother had severe complications during pregnancy and delivery
- History of asphyxiation at birth
- Have congenital structural malformation
- Have congenital metabolic disease
- Have major or genetic diseases that affect growth, development or cognition
- Have contraindications to MRI scanning
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Interventions
maternal exposure during pregnancy (e.g., environmental exposures and maternal inflammatory states)
Locations(1)
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NCT05040542