Individualized Systems Medicine Functional Profiling for Recurrent Glioblastoma

This trial uses lab testing of individual patient tumor cells to help personalize treatment for people with recurrent glioblastoma — a particularly aggressive brain cancer. A small piece of tumor tissue is tested against many drugs to find which ones are most likely to work for that specific patient. **You may be eligible if...** - You are between 18 and 70 years old - Your glioblastoma has come back (been histologically verified) - A biopsy can be performed to obtain enough live tumor cells for lab testing - You are ambulatory and in reasonably good health (ECOG 0–1) - Your bone marrow, liver, and heart function are adequate - You are able to give informed consent **You may NOT be eligible if...** - You are participating in another clinical trial that might interfere with this one - There is another medical reason that in the doctor's view makes participation unsafe or impractical Talk to your doctor to see if this trial is right for you.