Cerebral Embolization During Pulmonary Vein Isolation
Cerebral Embolization During Pulmonary Vein Isolation: an Observational Study
Charite University, Berlin, Germany
20 participants
Dec 1, 2021
OBSERVATIONAL
Conditions
Summary
The goal of the TCD-CA study is to determine the frequency of cerebral embolization during pulmonary vein isolation using continuous transcranial Doppler examination. Different parts of the procedure, different ablation techniques and periprocedural anticoagulation regimes will be compared.
Eligibility
Inclusion Criteria2
- patients with atrial fibrillation undergoing first-ever catheter-based ablation at Charité-Campus Benjamin Franklin
- age 18 years or older
Exclusion Criteria2
- pregnancy
- patient unable to provide written informed consent
Interventions
Patients undergoing different forms of pulmonary vein isolation are being monitored for microembolic signals (MES) by transcranial ultrasound. For standard ablation, a Thermocool Smarttouch SF (Biosense Webster) catheter will be used (50 W, target ablation index of 550).
Patients undergoing different forms of pulmonary vein isolation are being monitored for microembolic signals (MES) by transcranial ultrasound. For comparison, catheter ablation performed using very high power with a maximum of up tp 90 W (QMODE +) will be used.
Locations(1)
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NCT05048004