Ischemic Stroke Clinical Trials

393 recruitingLast updated: June 18, 2026

There are 393 actively recruiting ischemic stroke clinical trials across 61 countries. Studies span Not Applicable, Phase 3, Phase 2, Phase 4, Phase 1. Top locations include Beijing, Beijing Municipality, China, Beijing, China, Guangzhou, Guangdong, China. Updated daily from ClinicalTrials.gov.


Ischemic Stroke Trials at a Glance

393 actively recruiting trials for ischemic stroke are listed on ClinicalTrialsFinder across 6 cities in 61 countries. The largest study group is Not Applicable with 140 trials, with the heaviest enrollment activity in Beijing, Beijing, and Guangzhou. Lead sponsors running ischemic stroke studies include Capital Medical University, Beijing Tiantan Hospital, and Kafrelsheikh University.

Browse ischemic stroke trials by phase

Treatments under study

About Ischemic Stroke Clinical Trials

Looking for clinical trials for Ischemic Stroke? There are currently 205 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Ischemic Stroke trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Ischemic Stroke clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 393 trials

Recruiting
Not Applicable

Early Closure of Left Atrial Appendage for Patients With Atrial Fibrillation and Ischemic Stroke Despite Anticoagulation Therapy

Atrial FibrillationIschemic Stroke
Insel Gruppe AG, University Hospital Bern482 enrolled29 locationsNCT05976685
Recruiting

Cerebrospinal Fluid Mitochondrial Biomarkers in Ischemic Stroke and Alzheimer Disease

Ischemic StrokeAlzheimer Disease (AD)
Capital Medical University40 enrolled1 locationNCT07600996
Recruiting
Phase 3

rhTNK-tPA for Acute Ischemic Stroke Under Simplified Imaging in the Extended Time Window

Acute Ischemic Stroke
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University750 enrolled1 locationNCT07606807
Recruiting
Not Applicable

Goal Attainment Scaling in Upper Limb Spasticity Treatment

Ischemic StrokeHemorrhagic Stroke
University Rehabilitation Institute, Republic of Slovenia70 enrolled1 locationNCT04975646
Recruiting
Not Applicable

Proprioceptive Error Correction for Post-Stroke Upper Limb Rehabilitation

Ischemic StrokeProprioception
Sungkyunkwan University3 enrolled1 locationNCT07156955
Recruiting
Phase 3

Assess the Safety and Efficacy of Sovateltide in Patients With Acute Cerebral Ischemic Stroke

Acute Ischemic StrokeCerebral Stroke
Pharmazz, Inc.514 enrolled55 locationsNCT05691244
Recruiting
Phase 3

Single Bolus Non-immunogenic Staphylokinase in Patients With Acute Ischemic Stroke Within 4.5-24 Hours of Symptom Onset

Ischemic Stroke, Acute
Supergene, LLC990 enrolled15 locationsNCT07324837
Recruiting
Phase 1Phase 2

A Study of ASP2246 for People Who Have Movement Problems Caused by Brain Injury After a Stroke

Chronic Ischemic Stroke
Astellas Pharma Inc84 enrolled2 locationsNCT07318714
Recruiting
Not Applicable

Large Artery Occlusion Treated in Extended Time With Mechanical Thrombectomy Trial

Acute Ischemic Stroke
Fudan University336 enrolled1 locationNCT05326932
Recruiting

Platelet Expression of FcγRIIa and Arterial Hemodynamics to Predict Recurrent Stroke in Intracranial Atherosclerosis

StrokeIschemic StrokeTIA+1 more
University of California, Los Angeles250 enrolled1 locationNCT05518305
Recruiting
Phase 3

A Study to Test if Tenecteplase Helps People to Recover From an Acute Stroke When Given More Than 4.5 Hours After the Person Was Last Seen Well

Acute Ischemic Stroke
Boehringer Ingelheim1,325 enrolled242 locationsNCT07361302
Recruiting
Not Applicable

Efficacy and Safety of Tenecteplase Intravenous Thrombolysis in Acute Posterior Circulation Ischemic Stroke Within 4.5-24 Hours After Onset

Acute Ischemic Stroke
The First Affiliated Hospital of University of Science and Technology of China406 enrolled1 locationNCT07094763
Recruiting

Study to Collect Real-world Performance and Safety Data on Penumbra System® in Population With Acute Ischemic Stroke (AIS).

Acute Ischemic Stroke AIS
Penumbra Inc.200 enrolled10 locationsNCT07107022
Recruiting
Phase 2

Fructose for Acute Ischemic Stroke

Acute Ischemic Stroke
Ji Xunming,MD,PhD46 enrolled1 locationNCT07626541
Recruiting
Phase 4

Lacunar Stroke hyperAcute Clinical Utilization of Novel Approach Regimens: Rt-PA vs. DAPT Randomised Clinical Trial

StrokeIschemic StrokeLacunar Stroke
Nippon Medical School500 enrolled28 locationsNCT07111559
Recruiting
Not Applicable

A Pivotal Study Evaluating Safety and Effectiveness of Adaptative Tip Catheter in Patients With Acute Ischemic Stroke

Ischemic Stroke
Neuravi Limited74 enrolled15 locationsNCT07367100
Recruiting
Phase 1Phase 2

Human Placenta-derived 3D Mesenchymal Stem Cells(Guojianqingke)

Acute Ischemic Stroke
Chinese PLA General Hospital24 enrolled1 locationNCT07635758
Recruiting
Phase 4

Stroke Prevention In Ischemic Stroke With Covert Atrial Fibrillation

Atrial FibrillationStrokeIschemic Stroke+1 more
Assistance Publique - Hôpitaux de Paris1,148 enrolled1 locationNCT06486792
Recruiting
Not Applicable

Virtual Stroke Units Versus Conventional Stroke Unit Care in Non-Thrombectomy-Candidate Patients: A Non-Inferiority Prospective Cohort Study

StrokeIschemic StrokeStroke Hemorrhagic
Hospital Universitario Virgen Macarena726 enrolled1 locationNCT07635498
Recruiting
Not Applicable

HBO After Thrombectomy for AIS With LVO

Acute Ischemic Stroke From Large Vessel Occlusion
Beijing Tiantan Hospital420 enrolled1 locationNCT07626450