RecruitingPhase 3NCT05053867
A Randomized Controlled Trial of Inhaled Tranexamic Acid for the Treatment of Pulmonary Hemorrhage in Cancer Patients
Sponsor
M.D. Anderson Cancer Center
Enrollment
60 participants
Start Date
Oct 14, 2022
Study Type
INTERVENTIONAL
Conditions
Summary
This is a drug study that will examine if inhaled tranexamic acid can improve mortality in patients with cancer-related pulmonary hemorrhage and respiratory failure as compared to usual care.
Eligibility
Min Age: 18 Years
Plain Language Summary
Simplified for easier understanding
This study tests whether inhaled tranexamic acid (a drug that helps stop bleeding, delivered as a fine mist through a breathing tube) can reduce or stop bleeding in the lungs of cancer patients who are on ventilators (breathing machines). Lung bleeding is a life-threatening complication in some blood cancer patients.
**You may be eligible if...**
- You are 18 or older with a diagnosed blood cancer (like leukemia or lymphoma)
- You are currently on a mechanical ventilator
- You have confirmed bleeding in the lungs (bloody secretions or confirmed by bronchoscopy)
- You or your legal representative can give consent
**You may NOT be eligible if...**
- You are not expected to survive more than 48 hours
- You have a do-not-resuscitate or comfort-care order in place
- Bleeding appears to be coming from the nose or mouth rather than the lungs
- You have a known clotting condition that increases stroke risk
Talk to your doctor to see if this trial is right for you.
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
DRUGtranexamic acid
Inhaled
OTHERUsual Care
Standard of Care
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05053867
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