RecruitingPhase 3NCT05053867

A Randomized Controlled Trial of Inhaled Tranexamic Acid for the Treatment of Pulmonary Hemorrhage in Cancer Patients


Sponsor

M.D. Anderson Cancer Center

Enrollment

60 participants

Start Date

Oct 14, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

This is a drug study that will examine if inhaled tranexamic acid can improve mortality in patients with cancer-related pulmonary hemorrhage and respiratory failure as compared to usual care.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether inhaled tranexamic acid (a drug that helps stop bleeding, delivered as a fine mist through a breathing tube) can reduce or stop bleeding in the lungs of cancer patients who are on ventilators (breathing machines). Lung bleeding is a life-threatening complication in some blood cancer patients. **You may be eligible if...** - You are 18 or older with a diagnosed blood cancer (like leukemia or lymphoma) - You are currently on a mechanical ventilator - You have confirmed bleeding in the lungs (bloody secretions or confirmed by bronchoscopy) - You or your legal representative can give consent **You may NOT be eligible if...** - You are not expected to survive more than 48 hours - You have a do-not-resuscitate or comfort-care order in place - Bleeding appears to be coming from the nose or mouth rather than the lungs - You have a known clotting condition that increases stroke risk Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DRUGtranexamic acid

Inhaled

OTHERUsual Care

Standard of Care


Locations(1)

M D Anderson Cancer Center

Houston, Texas, United States

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT05053867


Related Trials