RecruitingNCT05058846

Pilot Study of Pancreatic Cancer Screening

Sponsor

University of California, San Francisco

Enrollment

250 participants

Start Date

Jan 20, 2022

Study Type

OBSERVATIONAL

Conditions

Pancreatic Carcinoma

Summary

This study investigates how often abnormal findings from routine magnetic resonance imaging occur in people with genetic mutations in BReast CAncer gene. (BRCA), ataxia telangiectasia mutated gene (ATM), or PALB2 screened for pancreatic cancer. This study may lead to a greater understanding of cancer and potentially, improvements in cancer screening and treatment.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This pilot study screens people at high genetic risk for pancreatic cancer — those who carry certain inherited gene mutations — using blood tests and MRI scans to try to catch pancreatic cancer early, before symptoms appear. **You may be eligible if...** - You carry a known gene mutation in BRCA1, BRCA2, ATM, or PALB2 - You are at least 50 years old (or 18+ if you also have a family history of pancreatic cancer) - You can read and speak English and are willing to follow study procedures **You may NOT be eligible if...** - You currently have or previously had pancreatic cancer - You are pregnant Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREBiospecimen Collection

Undergo blood, tissue, and saliva collection

PROCEDUREMagnetic Resonance Cholangiopancreatography

Undergo MRCP

PROCEDUREMagnetic Resonance Imaging

Undergo MRI

PROCEDUREEndoscopic ultrasound

Undergo endoscopic ultrasound

OTHERQuestionnaires

Complete the following questionnaires: Pancreatic Cancer Knowledge Survey, Pancreatic Cancer Worry Scale, Disease Specific Perceived Risk Survey, eGene Questionnaire

Locations(1)

University of California San Francisco

San Francisco, California, United States

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NCT05058846

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