RecruitingNot ApplicableNCT05063331

Patient-Centered Outcomes in the Surgical Treatment of Uterovaginal Prolapse

Patient-Centered Outcomes of Sacrocolpopexy Versus Uterosacral Ligament Suspension for the Treatment of Uterovaginal Prolapse


Sponsor

University Hospitals Cleveland Medical Center

Enrollment

320 participants

Start Date

Dec 15, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

The purpose of this study is to compare two types of surgery for the treatment of uterovaginal prolapse to determine which surgery works best from a patient's perspective and has the lowest number of short-term and long-term complications.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 80 Years

Inclusion Criteria4

  • Women ≥ 18 years of age and ≤ 80 years of age
  • Have diagnosis of symptomatic uterovaginal prolapse
  • Have elected to undergo surgical management of uterovaginal prolapse after consultation with their physician
  • Are eligible for both minimally invasive supracervical hysterectomy with sacrocolpopexy (MI-SCH+SCP) and total vaginal hysterectomy with uterosacral ligament suspension (TVH+USLS)

Exclusion Criteria8

  • Patients who wish to undergo uterine sparing procedures
  • Body mass index BMI) \> 50
  • Previous hysterectomy or prior uterovaginal surgery
  • Have a diagnosis of neurogenic bladder, Parkinson's disease, multiple sclerosis, spinal cord injury, or cerebrovascular accident
  • Chronic indwelling urinary catheter
  • Urinary diversion of any type
  • Any condition or disorder that, in the opinion of the investigator, might prevent the subject from completing the study or interfere with the interpretation of the study results
  • Unable to speak, read, understand English

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Interventions

PROCEDUREMinimally invasive supracervical hysterectomy and sacrocolpopexy (MI-SCH+SCP)

Minimally invasive robotic or laparoscopic supracervical hysterectomy will be done, and the vaginal apex (including cervix) will be suspended utilizing sacrocolpopexy mesh to the anterior spinous ligament.

PROCEDUREVaginal hysterectomy with uterosacral ligament suspension (TVH+USLS)

The uterus will be removed vaginally and the vaginal apex will be suspended utilizing sutures in the uterosacral ligament.


Locations(7)

Mayo Clinic

Jacksonville, Florida, United States

Northwestern Medicine

Chicago, Illinois, United States

Duke University

Durham, North Carolina, United States

University Hospitals Cleveland Medical Center

Cleveland, Ohio, United States

MetroHealth Medical Center

Cleveland, Ohio, United States

Cleveland Clinic

Cleveland, Ohio, United States

University of Pittsburgh, UPMC Magee-Womens Hospital

Pittsburgh, Pennsylvania, United States

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NCT05063331


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