Effect of Inulin on Gut Microbiota and Gut Barrier in Chronic Kidney Disease
Investigating the Effect of Inulin on Gut Microbiota and Gut Barrier in Advanced Chronic Kidney Disease - a Randomised, Placebo-controlled Trial
Charite University, Berlin, Germany
40 participants
Feb 1, 2022
INTERVENTIONAL
Conditions
Summary
An adequate fiber intake is crucial for a well-balanced diet and reduces the risk of chronic diseases. However, nutritional recommendations for chronic kidney disease patients lead to an insufficient fiber intake with possible maladaptive effects on the gut microbiome. Therefore, we want to study the effects of a 35-day inulin supplementation on the gut microbiome, gut barrier function, bacterial metabolites and immune cell states in chronic kidney disease patients.
Eligibility
Plain Language Summary
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Interventions
1 sachet à 15 grams daily for 7 days, followed by 2 sachets à 15 grams daily for 28 days
1 sachet à 15 grams daily for 7 days, followed by 2 sachets à 15 grams daily for 28 days
Locations(1)
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NCT05071131