RecruitingPhase 2NCT05077735

Stereotactic Biopsy Split-Course Radiation Therapy in Diffuse Midline Glioma, SPORT-DMG Trial

Stereotactic Biopsy Split-Course Radiation Therapy - Diffuse Midline Glioma (SPORT-DMG)


Sponsor

Mayo Clinic

Enrollment

32 participants

Start Date

Oct 11, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

This phase II trial studies the clinical outcomes of hypofractionated radiation therapy in patients with diffuse midline gliomas. This study aims to change the way radiation is delivered, from giving 6 weeks of radiation all at once to giving 2 weeks of radiation. This may determine if there is a difference in the outcome of the treatment, and most importantly, the patients' quality of life.


Eligibility

Min Age: 1 Year

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Hypofractionated Radiation Therapy, a procedure called Magnetic Resonance Imaging, and others for people with diffuse midline glioma, h3 k27m-mutant. The study is currently recruiting participants at 2 locations. People eligible for this study include aged 1 Year and older.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

RADIATIONHypofractionated Radiation Therapy

Undergo hypofractionated radiation therapy

OTHERQuestionnaire Administration

Ancillary studies

PROCEDUREMagnetic Resonance Imaging

Undergo MRI

PROCEDUREComputed Tomography Scan

Undergo CT scan


Locations(2)

Mayo Clinic Hospital in Arizona

Phoenix, Arizona, United States

Mayo Clinic in Rochester

Rochester, Minnesota, United States

View Full Details on ClinicalTrials.gov

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NCT05077735


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