RecruitingNCT05081141

HHV8 and Solid Organ Transplantation

Screening for HHV8 Infection in Solid Organ Transplantation Donors, Candidates and Recipients

Sponsor

Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico

Enrollment

250 participants

Start Date

Sep 15, 2021

Study Type

OBSERVATIONAL

Conditions

HHV8 HHV8 Infection HHV8-Related Malignant Neoplasm Kaposi Sarcoma Lung Transplant; Complications Liver Transplant; Complications Kidney Transplant; Complications Castleman Disease

Summary

Solid organ transplant candidates will undergo serological screening for HHV8 at time of listing and transplantation. In the event of a recipient/donor mismatch R-/D+ or in the presence of a seropositive recipient (R+), blood levels of HHV8 DNA will be monitored together with specific IGRA for HHV8.

Eligibility

Min Age: 18 Years

Inclusion Criteria3

SOT DONORS:
all donors used for transplantation purposes (kidney, liver, lung), including living donors in case of kidney transplantation
All patients listed for solid organ transplantation (lung, liver and kidney)