An Enhanced Package of Care to Reduce Reduce Mortality in Advanced HIV Disease
A Community-based Phase III, Cluster Randomized Trial of Point-of-care CD4 Testing and Enhanced Screening and Prophylaxis in Advanced HIV Disease
Makerere University
2,400 participants
May 4, 2022
INTERVENTIONAL
Conditions
Summary
A community-based Phase III, cluster randomized trial that seeks to determine the 24 week survival with retention in care of point of care CD4 testing with visitect and an enhanced package of screening and prophylaxis for opportunistic infections among patients with advanced HIV disease.
Eligibility
Inclusion Criteria3
- Age \>18 years
- CD4\<200 cells/µL
- Ability and willingness to give informed consent for the enhanced package of care arm.
Exclusion Criteria2
- Known virologic suppression (viral load \<1000 copies/mL) within prior 3 months
- Cannot or unlikely to attend regular clinic visits
Interventions
The intervention is an improved package of care for patients with advanced HIV disease with point of care CD4 testing, more sensitive screening tests for opportunistic infections and more intensive pre-emptive treatment for opportunistic infections
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT05085171