RecruitingNot ApplicableNCT05088395

Analysis of Circulating Tumor mArkers in Blood 4 - ALCINA 4


Sponsor

Institut Curie

Enrollment

2,050 participants

Start Date

May 19, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

Multi-cohort exploratory prospective study. Participation in the ALCINA 4 study does not change the standard management of the patient, including the treatments administered. A sampling schedule will be set up for each cohort. Depending on the clinical context studied and the biomarkers studied and/or sought, the timing of blood samples will vary between cohorts. There may be up to 4 samples taken per patient for up to 12 or 18 months. If a specific tumor sample is required, it will be collected only once during the study.


Eligibility

Min Age: 18 Years

Inclusion Criteria11

  • Patient treated for cancer at one of the participating center
  • years old or higher
  • Signed informed consent form
  • Patient not deprived of their liberty or under guardianship (including temporary guardianship)
  • Patient covered by social security scheme
  • Patient with no compliance issue (related to geographical, social or psychological reasons) for study follow up
  • Other additional criteria will be defined (defining tumor type and clinical setting), by cohort
  • If a biopsy tumor sample is to be taken:
  • Tumor considered as accessible by biopsy (at the investigator's discretion).
  • Normal blood coagulation tests (if applicable, and in case of a non-superficial tumor lesion).
  • No anticoagulant or antiaggregant treatment for the biopsy.

Exclusion Criteria1

  • Pregnant and/or breast-feeding women depending on cohort.

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Interventions

OTHERBlood sample

Depending on the clinical context studied and the biomarkers studied and/or sought, the timing of blood samples will vary between cohorts. There may be up to 4 samples taken per patient for up to 24 months.

OTHERBiopsy

If a specific tumor sample is required, it will be collected only once during the study


Locations(2)

Institut Curie

Paris, France

Institut Curie

Saint-Cloud, France

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NCT05088395


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