RecruitingNCT05089747

CIRculating CANcer MAster-Protocol

MAster Protocol Studying the Impact of Blood Biopsy on Screening, Diagnosis, Diagnostic and Follow-up of Solid Cancer in Adult


Sponsor

Hospices Civils de Lyon

Enrollment

6,000 participants

Start Date

Dec 5, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

This exploratory study will focus on the development of the analyses of blood biomarkers to better understand the circulating biomarkers associated with cancer diagnosis, treatment efficacy and progressive disease


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • Adult (>18y)
  • Owing a social security insurance
  • Any solid cancer diagnosed by histopathology or cytology
  • Patient with blood sampling required as per standard of care
  • Informed consent signed

Exclusion Criteria5

  • Refusal to participate
  • No blood sampling required as per standard of care
  • Hemoglobin < 7g/dl (< 9g/dl if respiratory or cardiovascular disease history)
  • Heterologous blood transfusion in the last 48 hours
  • Weight under 20 kg

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Interventions

BIOLOGICALBlood sampling for biomarker analysis (microRNA, circulating DNA…)

From one to four blood samplings: at diagnosis, after the first cycle of treatment, end of treatment, progressive disease (or end of study).


Locations(7)

Service de Pneumologie Hôpital Louis Pradel / Groupement Hospitalier Est

Bron, France

Hôpital Edouard Herriot / Groupement Hospitalier Centre

Lyon, France

Service de Pneumologie Hôpital Croix-Rousse / Groupement Hospitalier Nord

Lyon, France

Service de Pneumologie Aigue Spécialisée et Cancérologie Thoracique Hôpital Lyon-Sud / Groupement Hospitalier Sud

Pierre-Bénite, France

Hôpital Lyon-Sud / Groupement Hospitalier Sud

Pierre-Bénite, France

Oncologie médicale Hôpital Lyon-Sud / Groupement Hospitalier Sud

Pierre-Bénite, France

Service de dermatologie Hôpital Lyon-Sud / Groupement Hospitalier Sud

Pierre-Bénite, France

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NCT05089747