Cryotherapy in the Treatment of Desmoid Tumors
Istituto Ortopedico Rizzoli
94 participants
May 20, 2021
INTERVENTIONAL
Conditions
Summary
Desmoid tumor is a benign neoplasm with an unpredictable course and a high rate of local recurrence if treated surgically. Therefore, over time the surgical approach has become conservative, preferring simple observation or medical therapy in case of disease progression through the use of hormonal therapy and low-dose chemotherapy. Since this neoplasm remains benign, our study aims to avoid chemotherapy in patients usually young through the use of a minimally invasive treatment such as cryotherapy.
Eligibility
Inclusion Criteria3
- histologic diagnosis of desmoid tumors
- age > 18 years
- abdominal and extra-abdominal desmoid tumors
Exclusion Criteria3
- contraindication to the procedure by the interventional radiologist in terms of tumor proximity to neurologic/vascular structures
- retroperitoneal desmoid tumors
- age < 18 years
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Interventions
The procedure involves general or peripheral anesthesia and percutaneous treatment under CT control with probes capable of forming ice spheres of up to 3 cm that will be used in sufficient number to treat the neoplasm completely.
Locations(1)
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NCT05091255