RecruitingNCT05101382

A Retrospective Protocol Empowering Precision Research in Colorectal Cancer (ALFAOMEGA-RETRÒ)


Sponsor

IFOM ETS - The AIRC Institute of Molecular Oncology

Enrollment

500 participants

Start Date

Oct 28, 2020

Study Type

OBSERVATIONAL

Summary

ALFAOMEGA-RETRÒ will be exploited to retrospectively collect clinical and imaging data and archival samples to be used for validation and correlative studies on markers discovered by cutting-edge translational projects within the AIRC5x1000 program "Insights into the evolving heterogeneity of colorectal cancer (CRC): from mechanism to therapies" (an ongoing multi-institutional research program).


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • Histologically-confirmed diagnosis of colorectal cancer (any stage).
  • Age \>18 years at the time of diagnosis.
  • Availability of clinically-annotated radio-imaging data and/or diagnostic Formalin-Fixed Paraffin Embedded (FFPE) blocks (surgical resections and/or tumor biopsies), or at least 10 slides (preferably 20). FFPE tissue blocks are always preferred to slides.
  • Verification that the patient could not be reached for informed consent in accordance with applicable national regulations.

Interventions

OTHERObservation

Retrospective Observation of standard clinical practice


Locations(13)

Ospedale Policlinico San Martino

Genova, GE, Italy

Fondazione IRCCS, Istituto Nazionale dei Tumori

Milan, MI, Italy

Niguarda Cancer Center - ASST Grande Ospedale Metropolitano Niguarda

Milan, MI, Italy

IRCCS Istituto Clinico Humanitas

Milan, MI, Italy

Istituto Oncologico Veneto (IOV)

Padua, PD, Italy

Azienda Ospedaliero Universitaria Pisana

Pisa, Pisa, Italy

Istituto di Candiolo - IRCCS

Candiolo, TO, Italy

Azienda Ospedaliero Universitaria San Luigi Gonzaga

Orbassano, TO, Italy

Azienda Ospedaliera Ordine Mauriziano

Torino, TO, Italy

Institut Català D'Oncologia (ICO)

L'Hospitalet de Llobregat, Barcelona, Spain

Hospital del Mar - Parc de Salut Mar

Barcelona, Spain

Vall d'Hebron Institute of Oncology (VHIO)

Barcelona, Spain

INCLIVA - Instituto de Investigatión Sanitaria

Valencia, Spain

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NCT05101382