RecruitingNCT05101382

A Retrospective Protocol Empowering Precision Research in Colorectal Cancer (ALFAOMEGA-RETRÒ)


Sponsor

IFOM ETS - The AIRC Institute of Molecular Oncology

Enrollment

500 participants

Start Date

Oct 28, 2020

Study Type

OBSERVATIONAL

Conditions

Summary

ALFAOMEGA-RETRÒ will be exploited to retrospectively collect clinical and imaging data and archival samples to be used for validation and correlative studies on markers discovered by cutting-edge translational projects within the AIRC5x1000 program "Insights into the evolving heterogeneity of colorectal cancer (CRC): from mechanism to therapies" (an ongoing multi-institutional research program).


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This is a retrospective research study using existing medical records and stored tumor tissue from colorectal cancer patients to improve precision medicine — helping researchers understand how imaging and tumor biology can better guide treatment decisions. **You may be eligible if...** - You have been diagnosed with colorectal cancer (any stage), confirmed by biopsy - You were older than 18 at the time of diagnosis - Your imaging data (CT or MRI scans) and/or stored tumor tissue samples are available for research - Researchers have confirmed you cannot be reached for standard consent, in line with local regulations **You may NOT be eligible if...** - The required imaging data or tissue samples are not available - You do not meet the inclusion criteria Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERObservation

Retrospective Observation of standard clinical practice


Locations(13)

Ospedale Policlinico San Martino

Genova, GE, Italy

Fondazione IRCCS, Istituto Nazionale dei Tumori

Milan, MI, Italy

Niguarda Cancer Center - ASST Grande Ospedale Metropolitano Niguarda

Milan, MI, Italy

IRCCS Istituto Clinico Humanitas

Milan, MI, Italy

Istituto Oncologico Veneto (IOV)

Padua, PD, Italy

Azienda Ospedaliero Universitaria Pisana

Pisa, Pisa, Italy

Istituto di Candiolo - IRCCS

Candiolo, TO, Italy

Azienda Ospedaliero Universitaria San Luigi Gonzaga

Orbassano, TO, Italy

Azienda Ospedaliera Ordine Mauriziano

Torino, TO, Italy

Institut Català D'Oncologia (ICO)

L'Hospitalet de Llobregat, Barcelona, Spain

Hospital del Mar - Parc de Salut Mar

Barcelona, Spain

Vall d'Hebron Institute of Oncology (VHIO)

Barcelona, Spain

INCLIVA - Instituto de Investigatión Sanitaria

Valencia, Spain

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NCT05101382


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