First in Human Study of TORL-1-23 in Participants With Advanced Cancer

This is a first-in-human study testing a new investigational drug called TORL-1-23 in people with advanced solid tumors, to find the safest dose and learn how the drug behaves in the body. **You may be eligible if...** - You have a confirmed advanced solid tumor (cancer that has spread or cannot be removed) - You have at least one measurable tumor on scans - You are in reasonably good health (ECOG performance status 0–1) - Your organ function (liver, kidneys, blood counts) meets required levels - Your prior cancer treatments were completed at least 2–4 weeks ago **You may NOT be eligible if...** - You have active, symptomatic brain metastases - Side effects from your prior treatments have not resolved - You have serious uncontrolled health conditions or active infections - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.