RecruitingNCT05107466

Quantification of Visually Evoked Cortical Potentials in Individuals With Hearing Loss


Sponsor

Dartmouth-Hitchcock Medical Center

Enrollment

100 participants

Start Date

Jul 28, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

This research is being done to determine whether a test that measures a "Visual Evoked Potential" can be used in a new way for individuals that have hearing loss. This test measures the participant's brain's response (so called "brain waves") to specific visual images. This study will help the investigators determine whether this test could be used to improve treatments for patients with hearing loss. The "Visual Evoked Potential" measurement test is already used in the investigator's Neurology clinic at Dartmouth Hitchcock Medical Center for various conditions to measure "early" brain responses that occur in the first 1-2 seconds after a new cue. Our research aims to explore your brain's response just after that early 1-2 second period by looking at a specific response called the "P300". The P300 wave is a brain response to new or different images or sounds. A visual evoked P300 has not been studied in individuals with hearing loss. The investigators will compare the results of this test to standard auditory tests, tests of cognitive function, and cochlear implant patient outcomes to explore how these factors can predict successful use of a hearing aid or cochlear implant.


Eligibility

Min Age: 18 Years

Inclusion Criteria13

  • Inclusion
  • Subjects will be recruited from the Otolaryngology/Audiology clinic at DHMC with the goal of enrolling subjects with a variety of degrees of hearing loss and central auditory processing dysfunction.
  • Age \> 18 y/o.
  • Current and new patients receiving care in the DHMC Otolaryngology clinic or from the employees of Dartmouth College, DHMC, and the community, will be included as allowed under COVID guidelines.
  • Exclusion
  • Patients with known brain pathology (e.g., CNS tumors, CVA diagnosis, etc…) will be excluded.
  • Patients with severe neurological or neuropsychological disorders will be excluded.
  • Patients with known seizure history will be excluded.
  • Patients with known blindness will be excluded.
  • The following special populations will not be included:
  • Adults unable to consent
  • Individuals who are not yet adults (infants, children, teenagers)
  • Prisoners

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Interventions

DIAGNOSTIC_TESTP300 Visually evoked potential

Measurement of the late cortical response, P300 potential to visually evoked stimuli using an oddball paradigm.


Locations(1)

Dartmouth Hitchcock Medical Center

Lebanon, New Hampshire, United States

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NCT05107466


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