RecruitingNot ApplicableNCT05109208

The Use of Ultrasound in Assessing Post-prostatectomy Erectile Dysfunction

Ultrasound Vibroelastography in Post-Prostatectomy Erectile Dysfunction

Sponsor

Mayo Clinic

Enrollment

10 participants

Start Date

Oct 2, 2023

Study Type

INTERVENTIONAL

Conditions

Prostate Adenocarcinoma

Summary

Researchers are trying to determine whether there is additional utility to using vibroelastography, a noninvasive ultrasound technique to evaluate for the presence of tissue fibrosis, in conjunction with standard penile duplex Doppler ultrasound to assess erectile function (recovery) after prostate cancer surgery.

Eligibility

Sex: MALEMin Age: 40 Years

Inclusion Criteria5

Age > 40 years
Clinically localized prostate cancer (American Urological Association Grade Groups 1-2; cT1c or cT2a-b; PSA < 10) without clinic or imaging evidence of localized extra-prostatic or metastatic disease (i.e. AUA low and favorable intermediate risk prostate cancer)
International Index of Erectile Function (IIEF) of ≥ 21 points at baseline (no or mild erectile dysfunction)
Patient-expressed interest in consultation for sexual function (erectile function) preservation/ optimization
Planned bilateral nerves-paring prostatectomy

Exclusion Criteria4

Moderate or severe ED based in IIEF criteria (score < 21)
History of prior pelvic or penile surgery
Current or prior androgen deprivation therapy
Planned non-nerve sparing prostatectomy

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

DIAGNOSTIC_TESTUlrasound Vibroelastography (UVE)

Ultrasound technique to quantitatively assess tissue stiffness (elasticity and viscosity) by applying vibration through a specialized probe (indenter).