Biomarkers for Ventilator-associated Pneumonia

This study collects samples from the airways of ICU patients who are on mechanical ventilators to look for biological markers (biomarkers) that can predict who will develop ventilator-associated pneumonia (VAP) — a serious lung infection that can occur when patients are on breathing machines. Early identification of patients at risk could allow doctors to intervene sooner and potentially save lives. You may be eligible if... - You have been admitted to an intensive care unit - You were intubated (placed on a breathing machine) within the last 24 hours - You are expected to need mechanical ventilation for at least 48 hours You may NOT be eligible if... - You require very high levels of oxygen (FiO2 above 70%) or very high ventilator pressure (PEEP above 15) - You have a severe blood clotting problem - You already have a lung infection at the time of ICU admission - You have severely elevated or unstable pressure inside your skull Talk to your doctor to see if this trial is right for you.