RecruitingNot ApplicableNCT05131685

Distal Radius Interventions for Fracture Treatment

Reduction and Nonreduction Treatment of Displaced Pediatric Distal Radius Fractures (Peds-DRIFT Trial - Distal Radius Interventions for Fracture Treatment)


Sponsor

Ann & Robert H Lurie Children's Hospital of Chicago

Enrollment

334 participants

Start Date

Apr 9, 2023

Study Type

INTERVENTIONAL

Conditions

Summary

This protocol describes a multicenter, prospective randomized superiority trial comparing functional outcomes between children treated with sedated reduction versus no formal reduction.


Eligibility

Min Age: 4 YearsMax Age: 10 Years

Inclusion Criteria7

  • Provision of signed and dated informed consent form by parent or legal guardian
  • Stated willingness to comply with all study procedures and availability for the duration of the study
  • Male or female, aged 4-10 years
  • Diagnosis of 100% dorsally displaced radius metaphyseal fracture with any or no ulna involvement
  • Fracture is less than 5cm from the distal radial growth plate
  • Willing to adhere to the immobilization regimen
  • Fracture is acute (occurred less than 10 days prior to consent and assignment of treatment arm AND with ability to be taken to operating room (OR) or reduced in the emergency department (ED)

Exclusion Criteria4

  • Physeal involvement of fracture
  • Presence of open fracture, pathologic fracture, neuromuscular disease, or metabolic disease
  • Fracture cannot be treated with acute reduction due to being older than 10 days
  • Patient and parents are unable to adhere to procedures or complete follow-up due to insufficient comprehension of consent form or surveys or developmental delay.

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Interventions

PROCEDUREReduction

closed reduction under conscious sedation followed by casting

PROCEDUREImmobilization

immobilization in cast without reduction


Locations(26)

Phoenix Children's Hospital

Phoenix, Arizona, United States

Children's Hospital of Los Angeles

Los Angeles, California, United States

University of California- Los Angeles Medical Center

Los Angeles, California, United States

Nemours Children's Hospital

Wilmington, Delaware, United States

Niklaus Children's Hospital

Miami, Florida, United States

Riley Children's Hospital

Indianapolis, Indiana, United States

Riley Children's

Indianapolis, Indiana, United States

Johns Hopkins Hospital

Baltimore, Maryland, United States

Boston Children's Hospital

Boston, Massachusetts, United States

TRIA Health Partners

Minneapolis, Minnesota, United States

Gillette Children's Specialty Healthcare

Saint Paul, Minnesota, United States

University of Mississippi Medical Center

Jackson, Mississippi, United States

University Hospital- Rutgers

New Brunswick, New Jersey, United States

University of New Mexico - Carrie Tingley

Albuquerque, New Mexico, United States

New York University-Langone Health

New York, New York, United States

Hospital of Special Surgery

New York, New York, United States

University of Rochester Medical Center

Rochester, New York, United States

Montefiore Medical Center

The Bronx, New York, United States

University of North Carolina at Chapel Hill

Chapel Hill, North Carolina, United States

Cincinnati's Children's Hospital

Cincinnati, Ohio, United States

University Hospitals Rainbow Babies & Children

Cleveland, Ohio, United States

Oregon Health and Science University

Portland, Oregon, United States

Children's Hospital of Philadelphia

Philadelphia, Pennsylvania, United States

Texas Scottish Rite Hospital for Children

Dallas, Texas, United States

Texas Children's Hospital

Houston, Texas, United States

The Hospital for Sick Children

Toronto, Canada, Canada

View Full Details on ClinicalTrials.gov

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NCT05131685