RecruitingNCT05139784

BeAT1D: Benign Autoimmunity and Type 1 Diabetes

Sponsor

Institut National de la Santé Et de la Recherche Médicale, France

Enrollment

740 participants

Start Date

Oct 24, 2022

Study Type

OBSERVATIONAL

Conditions

Type 1 Diabetes

Summary

National multi-center non-interventional case-control cohort study with collection of biological samples to characterize the autoimmune T and B lymphocytes involved in the development of type 1 diabetes.

Eligibility

Min Age: 1 Year

Plain Language Summary

Simplified for easier understanding

This study investigates how autoimmune processes contribute to type 1 diabetes and other hormonal conditions, by analyzing immune markers in people with and without diabetes. **You may be eligible if...** - You have type 1 diabetes (with insulin use started within 6 months of onset and/or positive autoimmune antibodies) - OR you have another form of diabetes or autoimmune hormonal disorder - OR you are a healthy person without diabetes (for comparison) **You may NOT be eligible if...** - You have a condition that could interfere with autoimmune or metabolic markers (unless this is the condition being studied) Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERBiosampling

Collection of blood and stool specimens; and collection of lymph node specimens for the group undergoing surgical lymphadenectomy.

Locations(17)

APHP Hôpital Avicenne

Bobigny, Île-de-France Region, France

APHP Hôpital J. Verdier

Bondy, Île-de-France Region, France

APHP Hôpital L. Mourier

Colombes, Île-de-France Region, France

Hôpital Sud Francilien

Corbeil-Essonnes, Île-de-France Region, France

Hôpital Mignot - Service de Pédiatrie

Le Chesnay, Île-de-France Region, France

Hôpital Mignot - Services de Diabétologie/Endocrinologie Adultes

Le Chesnay, Île-de-France Region, France

APHP Hôpital Kremlin-Bicêtre

Le Kremlin-Bicêtre, Île-de-France Region, France

APHP Hôpital Lariboisière