RecruitingNCT05146986

RibFix Blu Thoracic Fixation System Versus Non-surgical Treatment in Non-flail Chest Rib Fractures

Prospective Multi-center Comparative Study of RibFix Blu Thoracic Fixation System Versus Non-surgical Treatment in Non-flail Chest Rib Fractures


Sponsor

Zimmer Biomet

Enrollment

167 participants

Start Date

Jan 2, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

This is a prospective, multi-center, observational, cohort study involving skilled cardiothoracic surgeons who are experienced in implanting the treatment of non-flail chest rib fractures and the use of RibFix Blu Thoracic Fixation System.


Eligibility

Min Age: 18 Years

Inclusion Criteria5

  • Age 18 and above (inclusive)
  • Simple rib fracture with ≥ 3 consecutive ribs, and the broken ends showed clear displacements
  • Indicated for surgical repair of rib fractures using RibFix Blu Thoracic Fixation System or non-surgical treatment (analgesia and symptomatic management treatment)
  • Willing and able to complete scheduled follow-up evaluations as described in the study protocol
  • Has participated in the Informed Consent process and is willing and able to sign an Institutional Review Board or Ethics Committee (IRB/EC) approved Patient Information/ Informed consent Form (PICF)

Exclusion Criteria12

  • Flail chest rib fractures based on radiological or clinical findings
  • Previous rib fractures or pulmonary problems, requiring continuous oxygen use at home pre-trauma
  • Presence of any serious medical issues that placed patient in generally poor conditions such that he or she could not tolerate the surgery
  • Chest trauma associated with severe craniocerebral injury, abdominal organ injury, severe spinal injury, limb fracture, or pelvic fracture requiring long-term bed rest
  • Has serious medical disease that is a contraindication for general anesthesia, such as cerebral infarction, myocardial infarction and hemorrhagic syndrome
  • Any contraindications listed in the manufacturer's Instruction to use for RibFix Blu Thoracic Fixation System as per below:
  • Spanning a midline sternotomy
  • Active Infection
  • Foreign body sensitivity
  • Is known to be pregnant
  • Is a prisoner, known alcohol or drug user or mentally incompetent or unable to understand what participation in this study entails.
  • Participation in another surgical intervention that may influence any of the outcome parameters.

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Interventions

DEVICENon surgical and Surgical

For non-surgical group, patients will receive non-surgical treatment (analgesia and symptomatic management treatment). For surgical group, patients will receive surgical treatment using RibFix Blu Thoracic Fixation System.


Locations(5)

Hunter New England Health District

Sydney, New South Wales, Australia

Flinders Medical Centre

Bedford Park, South Australia, Australia

The Alfred (Alfred Health)

Melbourne, Victoria, Australia

Yonsei Wonju Severance Christian Hospital

Wŏnju, Gangwon-do, South Korea

Ajou University Hospital

Suwon, Gyeonggi-do, South Korea

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NCT05146986


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