RecruitingNot ApplicableNCT05149742

Deafness and Cognition in Middle-aged Adults

Impact of Severe to Profound Deafness on Cognitive Functions in Middle-aged Adults


Sponsor

Assistance Publique - Hôpitaux de Paris

Enrollment

180 participants

Start Date

May 24, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

A mild cognitive impairment was observed in 50% of cochlear implant candidates aged 65 years and over, compared to 5-19% in general population. No studies analysed cognition in patients younger than 65 years. The aim of our study was to compare cognitive function between patients with severe and profound hearing loss and patients with normal hearing in patients aged 45 to 64 years.


Eligibility

Min Age: 45 YearsMax Age: 64 Years

Plain Language Summary

Simplified for easier understanding

This study is examining the relationship between significant hearing loss and cognitive function in middle-aged adults. Researchers want to understand whether deafness contributes to cognitive decline, and how cochlear implants or other hearing interventions may help. **You may be eligible if...** - You are between 45 and 64 years old - You have severe to profound bilateral hearing loss (in both ears) that developed after learning to speak, and hearing aids do not provide adequate speech understanding - OR you have normal hearing and are matched to a patient in the study by age, sex, and education level (as a control participant) **You may NOT be eligible if...** - You have a disability that prevents you from completing cognitive tests - You have a history of neurological or psychiatric disorders, including meningitis - You are currently on psychotropic medications - You are considered a vulnerable subject under French research protection rules Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALCognitive and audiometry evaluation

For both Patients and controls: * Cognitive functions evaluation * Tonal and vocal audiometry * Self questionnaires


Locations(1)

Centre de Recherche en Audiologie (CReA) - Groupe Hospitalier Pitié-Salpêtrière

Paris, France

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NCT05149742