RecruitingNot ApplicableNCT05149742

Deafness and Cognition in Middle-aged Adults

Impact of Severe to Profound Deafness on Cognitive Functions in Middle-aged Adults


Sponsor

Assistance Publique - Hôpitaux de Paris

Enrollment

180 participants

Start Date

May 24, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

A mild cognitive impairment was observed in 50% of cochlear implant candidates aged 65 years and over, compared to 5-19% in general population. No studies analysed cognition in patients younger than 65 years. The aim of our study was to compare cognitive function between patients with severe and profound hearing loss and patients with normal hearing in patients aged 45 to 64 years.


Eligibility

Min Age: 45 YearsMax Age: 64 Years

Inclusion Criteria2

  • Cases: Patients aged between 45 to 64 years with severe to profound bilateral post-lingual sensorineural hearing loss with a maximum intelligibility of 70% (disyllabic words) in free-field silence with hearing aids at 60 dB SPL, current in french
  • Controls: normal hearing subjects matched on age, sex and education level

Exclusion Criteria4

  • Associated disability that prevents the tests from being performed
  • Past and current history of neurological and psychiatric disorders including meningitis
  • Psychotropic drug treatment
  • Vulnerable subject

Interventions

BEHAVIORALCognitive and audiometry evaluation

For both Patients and controls: * Cognitive functions evaluation * Tonal and vocal audiometry * Self questionnaires


Locations(1)

Centre de Recherche en Audiologie (CReA) - Groupe Hospitalier Pitié-Salpêtrière

Paris, France

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NCT05149742