RecruitingPhase 1NCT05152394

Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Exosomes for Parkinson's Disease

Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Exosome Intranasal Instillation for the Treatment of Parkinson's Disease


Sponsor

The Foundation for Orthopaedics and Regenerative Medicine

Enrollment

20 participants

Start Date

Aug 17, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This trial will study the safety and efficacy of intranasal instillation of cultured allogeneic adult umbilical cord derived mesenchymal stem cell exosomes for the treatment of Parkinson's Disease


Eligibility

Plain Language Summary

Simplified for easier understanding

This study is evaluating the safety of a treatment using exosomes (tiny particles released by stem cells) derived from umbilical cord tissue for patients with Parkinson's disease. The goal is to determine whether this therapy is safe and tolerable before exploring its effectiveness. **You may be eligible if...** - You have been diagnosed with Parkinson's disease - You are willing and able to understand and sign the consent form **You may NOT be eligible if...** - You have an active infection - You have active cancer - You have chronic failure of multiple organ systems - You are pregnant - You are a pre-menopausal woman not using contraception - You have had an organ transplant - You have a known allergy to sulfur - You are currently using blood-thinning (anticoagulant) medications - You are actively abusing drugs Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BIOLOGICALAlloEx

cultured allogeneic adult umbilical cord derived mesenchymal stem cell exosomes


Locations(1)

Medical Surgical Associates Center

St John's, Antigua and Barbuda

View Full Details on ClinicalTrials.gov

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NCT05152394


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